Stephan Grein
© Julia Bremser
Dr. Stephan Grein
ORCID iD 0000-0001-9524-6633
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Affiliations
  • Life and Medical Sciences Institute (LIMES)
Research topics
  • Machine Learning
  • Dynamic Modeling
Stephan Grein has been working as a postdoctoral researcher at the LIMES institute since June 2021 focusing on metaflammation. Previous studies include Bioinformatics and obtaining a master's and bachelor's degree by Goethe-University in Frankfurt/Main. Lately he was awarded a Ph.D. degree in Applied Mathematics by Temple University, Philadelphia, PA in December 2020 working on the detailed modelling and simulation of intracellular ion-dynamics in neurons linked to synaptic plasticity and learning processes by developing novel hybrid-dimensional and multi-scale models as well as novel hierarchical mesh generation techniques for neurons applicable to multigrid methods for the efficient numerical simulation of the developed models on high-performance computing infrastructure.
Selected publications

(2021) C. Mertens, M. Schnetz, C. Rehwald, S. Grein, E. Elwakeel, A. Weigert, B. Brüne, M. Jung. Iron-Bound Lipocalin-2 from Tumor-Associated Macrophages Drives Breast Cancer Progression Independent of Ferroportin: Metabolites 18(3)


(2020) S. Grein, G. Qi, G. Queisser. Density Visualization Pipeline: A Tool for Cellular and Network Density Visualization and Analysis: Front Comput Neurosci. 14


(2020) Z. Li, A. Biswas, J. Finkelstein, S. Grein, Y. Kapoor, M. Milewski, G. Queisser. Modelling Drug Absorption from the Dermis after an Injection. Journal of Pharmaceutical Sciences 110(3)


(2017) C. Mertens, J. Mora, B. Ören, S. Grein, S. Winslow,  K. Scholich, A. Weigert, P. Malström, C. Forsare, M. Fernö, T. Schmidt, B. Brüne, M. Jung. Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment: Oncoimmunology 7(3)


(2016) M. Breit, S. Stepniewski, S. Grein, P. Gottmann, L. Reinhardt, G. Queisser. Anatomically Detailed and Large-Scale Simulations Studying Synapse Loss and Synchrony Using NeuroBox:  Front Neuroanat. 10(8)


(2014) S. Grein, M. Stepniewski, S. Reiter, M.M. Knodel, G. Queisser: 1D-3D Hybrid Modelling - From Multi-Compartment Models to Full Resolution Models in Space and Time: Front Neuroinform. 8(68)

(2012) S. Wolf, S. Grein, G. Queisser. Employing NeuGen 2.0 to Automatically Generate Realistic Morphologies of Hippocampal Neurons and Neural Networks in 3D: Neuroinformatics 11(3)

Stephan Grein
© Julia Bremser
Dr. Stephan Grein

+49 (0) 228 73 62235

Endenicher Allee 64

53115 Bonn